What is creatine and what is it for?

Creatine is a natural substance synthesized in the liver, pancreas and kidney from amino acids.

It was identified in 1832 when French chemist Michel Eugène Chevreul discovered a component of the skeletal muscle system that he identified with the Greek name “kreas”, which means meat. Hence its name: creatine.

What is creatine made of?

Creatine is made up of methionine, arginine, and glycine and is distributed to tissues with high energy demands, such as the brain and muscles. In fact, approximately 95% of the body’s creatine is stored in the skeletal muscle.

On average, the body produces about 1 gram of creatine per day in young adults, while the rest is obtained through the diet.

Creatine is found naturally in many foods, particularly animal proteins such as meat and fish. Half a kilo of raw meat contains approximately 2.3 g of creatine, which will be stored in the muscles after consumption

The downside to this process is that cooking the meat denatures the creatine, so it’s difficult to get enough of it through the diet to demonstrate enough health benefits. Due to this limitation, supplementing with creatine can provide numerous benefits.

Fortunately, creatine is widely available as a nutritional supplement. It is one of the safest, most efficient and science-backed supplements.

Why is creatine important?

Creatine is a very important molecule for maintaining the cellular balance of adenosine triphosphate (ATP). ATP is the main carrier of energy to be used in processing, and it is essential in sports practice.

During exercise, ATP levels in muscle cells deplete rapidly (approximately 10 seconds), which results in symptoms such as lactic acid buildup, fibrillar tears, and can also lead to cramps.

What is phosphocreatine?

Phosphocreatine is the active form of creatine. In order to rapidly replenish ATP, muscle cells have reserves of phosphocreatine, a high-energy phosphate compound that can rapidly form ATP.

During periods of low energy demand, ATP can be used to convert creatine back to phosphocreatine for later use. This important «energy store» is what allows creatine to enhance exercise performance.

For this reason, creatines that contain phosphocreatine directly in their composition, such as Clonapure®, help the body use that extra energy more quickly and efficiently, eliminating the loading phase of creatine monohydrate, and acting from the first moment.


Graphic of Clonapure® VS creatine monohydrate performance

What is creatine for?

Essentially, the main function of creatine is to be stored in the form of phosphocreatine, a highly energetic substance with a very quick release. In fact, at high intensities, phosphocreatine is the main energy substrate used by muscles.

  • Improve exercise performance. As the muscle is less tired thanks to creatine, we will find ourselves before a greater performance and longer training sessions.
  • Increase muscle mass. Creatine helps a greater amount of fluid to accumulate inside the cells. This increase in muscle mass is completely free of fat.
  • Make greater efforts. Athletes will be able to train longer without their muscles getting tired or feeling as fatigued, which increases performance and muscle mass.
  • Muscle recovery. After a hard workout, creatine will speed up the recovery of muscle fibers by increasing muscle glycogen stores. Therefore, this also reduces the risk of injury

Creatine benefits

Creatine benefits


There are preliminary studies that suggest that creatine would also induce improvements in other fields. Among them:

  1. Sarcopenia. Age-related loss of muscle mass seems to improve with creatine intake. It seems to work best when combined with exercise to build muscle.
  2. Depression. Creatine may be beneficial in treating symptoms of depression and anxiety.
  3. Brain damage. Positive effects have been observed on brain function in patients with damage that leads to a lack of creatine in the body.
  4. Cognitive performance. Creatine can help in the resolution of cognitive tasks, particularly when carried out in situations of mental fatigue.
  5. Bone health in the elderly population. By combining creatine with resistance exercises, it can improve the quality of the bones of the elderly.


Clonapure® is a state-of-the-art sports supplement whose formula formula the real active form of creatine: phosphocreatine.

In fact, Clonapure® is the perfect combination of Creatine Monohydrate + Phosphocreatine + Phosphate, a unique combination that helps keep the phosphagen system active for longer.

Clonapure® composition

For this reason, Clonapure® is the only product on the market that gives immediate energy to the muscles, without a loading phase and acting from the first moment.




Creatine is widely regarded as one of the most popular supplements in the sports nutrition marketplace. It is mainly used by bodybuilders, and athletes, as

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